‘Supernatural’ Actor Nicki Aycox Dead at 47 Following Leukemia Battle

Nicki Aycox, the actor best known for portraying Meg Masters in Supernatural, has died. She was 47.

Aycox’s sister-in-law, Susan Raab Ceklosky, confirmed her death on Facebook on Nov. 17, where she wrote, “My beautiful, smart, fierce, incredibly talented, and loving sister-in-law, Nicki Aycox Raab, passed away yesterday with my brother, Matt Raab, by her side.”

She continued, “Nicki and Matt had a wonderful life together in California. She was definitely a fighter and everyone who knew her loved her.”

Ceklosky did not provide a cause of death or additional details. Aycox previously shared in 2021 that she had been diagnosed with leukemia. She wrote on Instagram at the time, “I’m doing incredibly well and fighting my way thru chemo,” and continued to provide updates to her followers.

In her final Instagram post, which she shared March 25,  Aycox sang “Here We Go Again” by Whitesnake after undergoing treatment. She captioned the post, “DO NOT attempt to sing 80’s music after taking high doses of chemo will cause memory loss. Literally got not 1 lyric correct.”

Aycox starred in the popular CW series Supernatural for two seasons, where she starred opposite Jared Padalecki and Jensen Ackles for five episodes. Her other acting credits include appearances in single episodes of Law & Order and CSI: Miami, as well as a lead role in TNT’s Dark Blue, which she starred in alongside Dylan McDermott and Omari Hardwick.

While she had plenty of TV credits to her name, Aycox also appeared in multiple horror movies, including Jeepers Creepers 2, Dead Birds and Perfect Stranger.

Supernatural creator Eric Kripke shared a tribute to Aycox on Twitter Sunday, writing, “Gutted to hear the great #NickiAycox, our first #MegMasters, passed away. Too young. She was a delight & delivered lines like honey & venom. I marvel at how she made a simple word like ‘lackluster’ legendary.”

Fans chimed in with fond memories of their own. One wrote, “Meg was so deceptively & diabolically dangerous. Then when we saw the human Meg ghost in Are You There, God? It’s Me, Dean Winchester she was so sweet & vulnerable. Nicki gave us all the flavors & it was exquisite to watch her perform.”

Another added, “She was perfection in the role. So natural. Believable as innocent and evil. Whoever decided to make her a gorgeous short-haired character – good call. You don’t have to have Barbie hair. So sad she’s gone.”